Anfield (Saturday, 3pm)
Liverpool team news:
Defender Daniel Agger is expected to return to face Southampton after missing Monday's draw at Swansea with a side strain.
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Ready: Daniel Agger (left) has shrugged off a side strain and is available
Playmaker Philippe Coutinho is out for several weeks after undergoing a shoulder operation so the likes of Iago Aspas and Raheem Sterling will be pushing for a recall.
The match marks the completion of striker Luis Suarez's 10-game ban, which carried over from last season.
Team (from): Mignolet, Wisdom, Toure, Agger, Enrique, Lucas, Gerrard, Henderson, Moses, Aspas, Sterling, Sturridge, Jones, Skrtel, Kelly, Alberto, Allen, Ibe.
Southampton team news:
Left-back Luke Shaw is fit for the Barclays Premier League trip to Liverpool.
The teenager limped off in last weekend's 0-0 draw with West Ham, but Mauricio Pochettino has revealed he has overcome that knock.
Fellow left-back Danny Fox remains a doubt with an ankle complaint and Tadanari Lee may also miss out.
Team (from): Boruc, Davis, Gazzaniga, Clyne, Chambers, Shaw, Fox, Lovren, Hooiveld, Yoshida, Fonte, Schneiderlin, Cork, Davis, Ward-Prowse, Wanyama, Lallana, Rodriguez, Ramirez, Do Prado, Osvaldo, Lambert, Lee.
In contention: Luke Shaw limped off against West Ham but is fit enough for the trip to Liverpool
Big match stats:
Daniel Sturridge is the first player in Liverpool's Premier League history to score in the team's opening four games of the season.
Southampton have won four of the last six Barclays Premier League games against Liverpool, but the Reds have won the last two at Anfield by a 1-0 scoreline.
In the last five Premier League meetings between the Saints and Liverpool, the Merseysiders have scored three goals, all between the 43rd and 45th minutes.
Southampton have scored just four goals in their last nine Barclays Premier League matches.
The Saints have played three teenagers in two of their Premier League fixtures this season, something Liverpool did six times last season (a divisional high).
Lucas has been booked in each of his last three Premier League appearances. He has never been booked in four successive PL games.
Trouble: Lucas has been booked in each of his last three league games
Southampton have averaged the second highest possession figure this season (59.1%), Liverpool are only ninth (48.1%).
Southampton have allowed only nine shots on target this season - fewer than any other side, while Liverpool have conceded the second most (22).
Sturridge has scored the third and fourth fastest goals of the season so far (versus Man Utd and Swansea respectively).
Rickie Lambert has had eight headed shots in the Premier League this season; three more than Liverpool have in total (5).
All five of Liverpool's goals in the Barclays Premier League this season have come before half-time.
*Stats supplied by Opta